The Importance of Extended-Spectrum β-lactamases in Gram-Negative Enteric Bacilli and the Phenotypic Methods of detection

Authors

  • Akbar Mirsalehian Professor, Department of Microbiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  • Davood Kalantar-Neyestanaki Assistant Professor, Department of Microbiology, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran
  • Fereshteh Jabalameli Assistant Professor, Department of Microbiology, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
  • Mehdi Fatahi-Bafghi Assistant Professor, Department of Microbiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  • Mohammad Eman eini Associate Professor, Department of Microbiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  • Shahla Mansouri Professor, Department of Microbiology, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran
Abstract:

The production of β-lactamase enzymes is the main mechanism of resistance to β-lactam antibiotics in gramnegative bacilli. Therefore, it is important to identify the β-lactamases-producing bacteria for the treatment of caused infections. This article aimed to review the recent literature and guidelines regarding phenotypic detection of β-lactamases in common gram-negative bacilli in clinical samples.

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Journal title

volume 23  issue 3

pages  380- 405

publication date 2016-07-01

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